Showing posts with label cholesterol. Show all posts
Showing posts with label cholesterol. Show all posts

Thursday, September 25, 2025

Health Effects Of A Low Sodium Diet


AUTHORS' CONCLUSIONS:
Sodium reduction from an average high usual sodium intake level (201 mmol/day) to an average level of 66 mmol/day, which is below the recommended upper level of 100 mmol/day (5.8 g salt), resulted in a decrease in SBP/DBP of 1/0 mmHg in white participants with normotension and a decrease in SBP/DBP of 5.5/2.9 mmHg in white participants with hypertension. A few studies showed that these effects in black and Asian populations were greater. The effects on hormones and lipids were similar in people with normotension and hypertension. Renin increased 1.60 ng/mL/hour (55%); aldosterone increased 97.81 pg/mL (127%); adrenalin increased 7.55 pg/mL (14%); noradrenalin increased 63.56 pg/mL: (27%); cholesterol increased 5.59 mg/dL (2.9%); triglyceride increased 7.04 mg/dL (6.3%).

Low sodium helps decrease blood pressure but for some reason cholesterol and triglycerides were increased. More study is required.

Thursday, April 21, 2022

Melatonin For Resistance-Training Athletes

Can melatonin have beneficial effects for athletes other than on circadian rhythms?  This paper says yes.  Abstract:

Previous data showed that the administration of high doses of melatonin improved the circadian system in athletes. Here, we investigated in the same experimental paradigm whether the antioxidant properties of melatonin has also beneficial effects against exercise-induced oxidative stress and muscle damage in athletes. Twenty-four athletes were treated with 100 mg.day-1 of melatonin or placebo 30 min before bedtime during four weeks in a randomized double-blind scheme. Exercise intensity was higher during the study that before starting it. Blood samples were collected before and after treatment, and plasma was used for oxygen radical absorption capacity (ORAC), lipid peroxidation (LPO), nitrite plus nitrate (NOx), and advanced oxidation protein products (AOPP) determinations. Glutathione (GSH), glutathione disulphide (GSSG) levels, and glutathione peroxidase (GPx) and reductase (GRd) activities, were measured in erythrocytes. Melatonin intake increased ORAC, reduced LPO and NOx levels, and prevented the increase of AOPP, compared to placebo group. Melatonin was also more efficient than placebo in reducing GSSG.GSH-1 and GPx.GRd-1 ratios. Melatonin, but not placebo, reduced creatine kinase, lactate dehydrogenase, creatinine, and total cholesterol levels. Overall, the data reflect a beneficial effect of melatonin treatment in resistance-training athletes, preventing extra- and intracellular oxidative stress induced by exercise, and yielding further skeletal muscle protection against exercise-induced oxidative damage.

This, melatonin seems to protect skeletal muscle from oxidative stress damage as it prevents extracellular and intracellular oxidative stress. Interestingly, total cholesterol was reduced as well.

Tuesday, November 14, 2017

The New Blood Pressure Guidelines

The blood pressure guidelines for “high blood pressure” have been lowered once again. As America get fatter and fatter, it’s interesting that the cutoffs for things like blood pressure and cholesterol levels get lower and lower, and drug sales go higher and higher.

New guidelines lower the threshold for high blood pressure, adding 30 million Americans to those who have the condition, which now plagues nearly half of U.S. adults.
High pressure, which for decades has been a top reading of at least 140 or a bottom one of 90, drops to 130 over 80 in advice announced Monday by a dozen medical groups.

I’m skeptical of these new blood pressure standards.  If the ultimate outcome – regardless of what people are saying now – is really going to be an emphasis on losing weight, exercise, and good diets, then fine.  But I believe that the real ultimate outcome is going to be putting half of America, or more, on blood pressure medication, just like we’ll have half on statins, and a big percentage on attention deficit disorder medication, all leading to fat profits for pharmaceutical companies.

So, yes, get your blood pressure to healthy levels. But the specter of folks with 30+ BMIs taking blood pressure medications and statins seems to be self-defeating.

Sunday, May 21, 2017

Diet Vs. Drugs

In general, I believe that, when and where appropriate, lifestyle changes should be tried first before taking drugs to deal with certain common types of chronic metabolic disorders (but of course always consult with your physician, as "in general" does not apply to every specific case). The experts agree with my opinion:

Many Americans, when faced with a serious health risk like high cholesterol, opt to take a pill rather than adopt healthier living habits.

A middle-aged woman I know is typifies this attitude. Thrilled with how well medication has controlled her rising cholesterol level, she continues to indulge in foods rich in cholesterol-raising saturated fats. She also carries around more body fat, especially risky abdominal fat, than is considered healthful.

I met people like that. For example, some people with Type II Diabetes believe that taking medication gives them green light to load up with cookies, cakes, and doughnuts.
Dr. Philip Greenland, a cardiologist and epidemiologist at Northwestern University Feinberg School of Medicine, said, “People should be following a heart-healthy diet, keeping their weight under control and exercising regularly. This would be a highly preferable approach. Unfortunately, it’s not the direction we’re going in.”

Admittedly, swallowing a little pill every day is simpler than changing one’s behaviors — and especially one’s eating habits. Yet experts like Dr. Greenland say that even when taking a statin or some other cholesterol-lowering drug, changes in diet and exercise habits are needed to maximize the drug’s benefits. He and others insist that drugs should be a last resort, after lifestyle changes fail to lower serum cholesterol adequately.
I agree. Unfortunately, Dr. Greenland is correct that this is not the direction we are going on. Everything and everyone needs to be medicated, it seems. I recently read a suggestion stating that drugs for treating the consequences of obesity are needed, since it is unrealistic to think people are going to lose weight. In other words, eat excessively, be obese, and then take a pill to try and evade the consequences. Of course, all of these drugs have side effects.  Wouldn’t it be easier to attack the problem rather than its consequences?  Lifestyle changes involving diet and exercise may help the underlying problem, and do so without expensive medications and their side-effects.
Noting that “every food a person might eat either fights or contributes to disease,” Dr. Kopecky said his clinic “tries to get everyone on a Mediterranean diet,” the traditional eating habits of people living in Greece and southern Italy. In addition to its heart benefits, studies suggest the Mediterranean diet may “reduce the risk of Alzheimer’s disease, cancer, Parkinson’s disease, diabetes, arthritis and the metabolic syndrome”… “people in Greece eat an average of nine servings a day of antioxidant-rich fruits and vegetables,” and the booklet outlines a long list of potentially healthful foods. Some examples include prunes, blueberries, red grapes, oranges, strawberries, kale, spinach, brussels sprouts, broccoli, beets, red bell peppers, corn and eggplant.

At a minimum, Americans should strive to consume two or more servings of vegetables and two to three or more servings of fresh fruit each day. If “fresh” is not available, “fresh frozen” is the next best option.

Living near the sea, Mediterraneans eat lots of seafood, often daily, and the Mayo diet recommends three or more servings a week of fish or shellfish. One or more servings should be a fatty fish rich in protective fish oils, like salmon, tuna, bluefish, sardines, mackerel and trout.
The white meat of chicken or turkey, eaten without the skin, is the land animal protein of choice, the Mayo Clinic says, with a serving size limited to 3 ounces of cooked meat, about the size of a deck of cards.

Unlike many Americans, people living along the Mediterranean also consume lots of foods with vegetable protein: legumes like split peas, lentils and peanuts, and beans like lima, black, red, kidney and navy…Whole grain breads and cereals are part of the recommended diet, but note that a serving of bread is one slice. Breads should be eaten plain or dipped in olive oil, the Mayo booklet says.

Which brings us back to fats. Olive oil, especially extra-virgin and virgin, the least processed forms, or canola oil should be used in place of butter or margarine…Eggs are back in fashion, consumed in moderation. That means a limit of three to four egg yolks a week, though no limit on egg whites. A good trick when preparing an omelet or scrambled eggs is to use two egg whites for every one yolk…However, red and processed meats should be limited to one three-ounce serving a week. And those cherished treats and desserts — pastries, cakes, doughnuts, cookies, pudding, French fries, potato chips and all sweetened and diet carbonated soft drinks — are best avoided altogether…Likewise, avoid high-fat dairy products…

Of course, what you eat is only half of the health-saving story. Regular physical exercise is a critical ingredient, even if it doesn’t result in weight loss. “Fitness trumps fatness,” Dr. Kopecky said, adding that being fit even while remaining fat markedly reduces cardiovascular risk. He urges parents to establish heart-healthy habits early in their children’s lives. “Patterns for physical activity are set by ages 6 to 9, and healthy eating habits by ages 9 to 12; together, they can result in a much lower risk for developing heart disease as adults,” he said.
This is all sound advice. If radical changes are considered too difficult at first, then go slowly. Reduce rather than eliminate the more unhealthy foods and continue to reduce their intake over time, until they are eliminated or are taken at a reasonable and acceptable frequency. Gradually increase your intake of fruits, vegetables, and whole grains. Increasingly incorporate physical activity into your daily regimen. Over time, you will have reached the required goals and objectives.

Thursday, December 3, 2015

Breakfast Protein: Egg Whites


New studies show that eating whole eggs, in moderation, may not be bad for the health of most people, and can actually have benefits. The yolk is enriched in vitamins and has protein, and I do occasionally eat whole eggs.

However, in order to get some breakfast protein without the fat and cholesterol of the yolk, I eat egg whites a couple of days per week. I buy the small cartons of pasteurized egg whites. Once opened, these cartons should be used within a week. These egg whites can be microwaved, and I like to prepare mine in advance. I put ½-2/3 of one small carton into a microwave-safe bowl, and cover with plastic wrap. Microwave on high one to one-and-a-half minutes (1:00-1:30), stir with a spoon, repeat, stir again with a clean spoon, repeat as required so the whole bit is completely cooked, without liquid even at the bottom of the bowl. Depending upon how much I cook at one time, it takes between 2:30-3:30 minutes. The cooking time, of course, also depends on the power of the microwave and the dimensions and shape of the bowl.

Cooked egg whites can last several days in the fridge. I also freeze batches. True, they may be a bit rubbery once thawed out (and I thaw them in the microwave on top of a paper towel on a microwave-safe dish; the paper towel is to soak up any excess water from the freeze-thaw), but they are edible and the difference in taste and texture to non-frozen is slight.

One meal idea is to warm the cooked egg whites and melt a slice of non-fat cheese on top. Then put the egg white-cheese mixture inside of a toasted 100% whole wheat bagel with a bit of Smart Balance and some red pepper hot flakes (or other seasoning). This is an excellent high-protein, law-fat, high fiber breakfast with added calcium.

One note: egg whites are enriched in avidin, which binds biotin. Frequent consumption of raw egg whites can cause a serious biotin deficiency. Cooking inactivates most of the avidin in egg whites, but not completely; therefore, consumption of a large amount of egg whites on a frequent basis may cause a biotin deficiency. Actually, egg yolks are an excellent source of biotin, another reason why whole eggs in moderation can be a good choice.

Plain non-fat Greek yogurt is another way of obtaining breakfast protein. Those who are lactose intolerant can often eat moderate amounts of yogurt, especially yogurt with live cultures that help break down lactose.

Saturday, October 24, 2015

Fructose - Your Foe

We all know that sugar is bad for us. This is why the World Health Organization recommends us to limit our sugar (sucrose) intake to six teaspoons a day. But did you know that fructose, one of the individual types of sugar, is toxic for you? You may not be aware that you consume fructose every day. It is present in regular sugar “sucrose” (composed by glucose and fructose at a ratio of 1:1); however, its main source in the diet is the omnipresent high fructose corn syrup. This “syrup” is added to almost everything: from soft drinks, candy, bread, to tomato soup and ketchup. It is even in some potato and macaroni salads in the neighborhood deli. The fruit juices also contain considerable levels of fructose.
 

Whereas the sugar glucose is used as an energy source by every single cell in the body, fructose is not. Be aware, however, that excess of glucose intake could be converted into fructose in the body. Unlike glucose, fructose can be utilized only by liver cells, where fructose processing results in increased levels of the toxic uric acid and fat. Thus, excess of fructose intake from the diet results in excess fat in the liver (and “fatty liver” disease) and excess fat circulating in the blood. The increased fat in the blood accumulates in the body, and leads to obesity, cardiovascular (heart) diseases, and type 2 diabetes. In fact, fructose is the main culprit for metabolic syndrome, the condition in which high blood pressure, high blood sugar, excess body fat around the waist, and high cholesterol levels co-occur.


Actionable

  • Read the ingredients of each food product in your refrigerator and pantry. If “high fructose corn syrup” is one of the ingredients, discard the product. Stop buying such products.
  • Stop drinking soft drinks and fruit juices. Instead, eat fruit and drink water.
  • Laugh with this Coca Cola video. Coca Cola is one of the companies that have drowned us in drinks with high fructose corn syrup and sugar.
  • Next time you want to eat out, think twice: do you know what is in your meal? The only way to be sure is to cook it yourself. Learn how to cook with these affordable recipes from the free Good and Cheap cookbook.
  • If you do eat out and you are served in a plate larger than 9 inches in diameter, chances are that there is too much food. Eat only half of the meal and take the other half home.