The taste is divine if you like smoked cheese!
The recipe below is for two pizzas, eight slices total. Maybe will feed four people.
Ingredients for the dough
4 cups flour
2 cups warm water
1 pack instant yeast
1 teaspoon salt
Ingredients for the topping
10.5 oz cream of mushroom (condensed soup)
1 Tbsp olive oil
black pepper
salt to taste
1 lb mushrooms
smoked cheese (approximately 0.3 lb)
Directions
Prepare the dough the day before baking the pizza. Mix the flour and salt in a large bowl. Make a well in the middle of the flour, sprinkle the yeast and pour the warm water. Incorporate the flour by hands to a soft ball of dough. Oil the bowl and leave the dough covered with Saran wrap and a towel in a warm place. The next day, divide into two parts and spread on two oiled cookie sheets (press the dough into a thin layer with your hands until the dough covers most of the sheets). Leave the dough at room temperature to rise again for an hour.
For the topping, clean and cut the mushrooms. Soften them in oil for 10 minutes. Keep the cover on to preserve most of the liquid. Remove from the stove and mix with the condensed soup. Spread on the pizza dough. Add pieces of smoked cheese on top and bake for 20 minutes or less at 400°F.
Cancer is the leading cause of morbidity and mortality around the globe. For certain types of cancer, chemotherapy drugs have been extensively used for treatment. However, severe side effects and the development of resistance are the drawbacks of these agents. Therefore, development of new agents with no or minimal side effects is of utmost importance. In this regard, natural compounds are well recognized as drugs in several human ailments, including cancer. One class of fungi, "mushrooms," contains numerous compounds that exhibit interesting biological activities, including antitumor activity. Many researchers, including our own group, are focusing on the anticancer potential of different mushrooms and the underlying molecular mechanism behind their action. The aim of this review is to discuss PI3K/AKT, Wnt-CTNNB1, and NF-κB signaling pathways, the occurrence of genetic alterations in them, the association of these aberrations with different human cancers and how different nodes of these pathways are targeted by various substances of mushroom origin. We have given evidence to propose the therapeutic attributes and possible mode of molecular actions of various mushroom-originated compounds. However, anticancer effects were typically demonstrated in in vitro and in vivo models and very limited number of studies have been conducted in the human population. It is our belief that this review will help the research community in designing concrete preclinical and clinical studies to test the anticancer potential of mushroom-originated compounds on different cancers harboring particular genetic alteration(s).
