Saturday, January 28, 2017

Probiotics For Clostridium Difficile Prevention?

At left, how probiotics work; By Rachelshoemaker - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=54240651

Clostridium difficile is a common cause of acquired GI infections in the medical setting, often cuaing severe diarrhea. There is a school of thought that suggests that colonizing the gut with beneficial bacteria can inhibit infection with harmful bacterial species. This study suggests "moderate quality evidence" that probiotics can be used to prevent diarrhea from Clostridium difficile.  The conclusions from their abstract:

AUTHORS' CONCLUSIONS:
Based on this systematic review and meta-analysis of 23 randomized controlled trials including 4213 patients, moderate quality evidence suggests that probiotics are both safe and effective for preventing Clostridium difficile-associated diarrhea.

If supported by further research, this would certainly be welcome news, to reduce the incidence of the severe problems that accompany these sorts of infections, and once again demonstrates the positive value of a proper gut microbiota.


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