Friday, September 1, 2017

Gut Microbiota And Chemotherapy Resistance

https://www.hgsc.bcm.edu/fusobacterium-nucleatum-atcc10953 

Here, at the link, is another paper discussing the importance of gut microbiota to human disease. In this paper, we learn that the bacterial species Fusobacterium (F.) nucleatum is abundant in colorectal cancer tissue of patients exhibiting disease recurrence post chemotherapy.  It was shown that these bacteria promote resistance to anti-colon cancer chemotherapy by targeting particular signaling pathways.  These findings may lead to novel therapies to prevent and/or reverse resistance to chemotherapy. The findings also stress the importance of having an optimal gut microbiotic profile for better health and, if sickness does occur, optimal disease management.

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