Here is an article outlining the dangers of shift/nigh work to human health.
Shift/night work disrupts normal circadian (internal timing) rhythms, affecting sleep and promoting disorders “including cancer, diabetes, cardiovascular risks, obesity, mood disorders and age-related macular degeneration. “ Melatonin secretion may be involved. The paper suggests “melatonin, bright light, or psychotropic drugs, have been proposed as a means to combat circadian clock disruption and improve adaptation to shift and night work.”
If you can at all avoid shift/night work do so; if you cannot because of work requirements then discuss with your physician strategies to adjust and hopefully reduce the risk of serious heath disorders consequent to disruption of normal life rhythms.