Showing posts with label stem cells. Show all posts
Showing posts with label stem cells. Show all posts
Thursday, December 19, 2024

Identifying And Targeting Cancer Stem Cells

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Here is a paper from several years ago demonstrating further identification of (colon) cancer stem cells, with information on targeting suc...
Thursday, February 18, 2021

Prevent Aging With Stem Cell Rejuvenation?

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Discussion of a possible anti-aging approach , abstract: Characterized by dysfunction of tissues, organs, organ systems and the whole o...
Monday, July 1, 2019

Lessons From Mice And Flies

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On Wnt signaling , abstract: Adult stem cells play critical roles in the basal maintenance of tissue integrity, also known as homeost...
Monday, June 3, 2019

Low Oxygen And Osteogenic Differentiation

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Low oxygen conditions can affect the differentiation of bone precursor cells.  Abstract: This study examined the effects of low oxyg...
Tuesday, November 13, 2018

Another Useful Phytochemical

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A phytochemical can suppress dangerous cancer stem cell qualities in liver cancer by inhibiting Wnt signaling; abstract: The hierarch...
Friday, August 17, 2018

Cancer Stem Cells And Lipid Metabolism

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Cancer stem cells seem to have an increased reliance on lipid metabolism , which can be a target for anti-cancer therapy.  I wonder if this...
Monday, August 13, 2018

Blood Stem Cell Hierarchy

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Blood stem cells seem to have preferences to what they will differentiate into, including the “multipotent” stem cells that typically have ...
Saturday, June 30, 2018

CRISPR Editing In Blood Stem Cells

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CRISPR editing in blood stem cells ; abstract: Genome editing via homologous recombination (HR) (gene targeting) in human hematopoieti...
Monday, June 25, 2018

p53 Inhibits CRISPR-Cas9 Engineering In Human Pluripotent Stem Cells

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Human pluripotent stem cells are difficult to engineer with the CRSPR system compared to other cell types, which is unfortunate given the g...
Saturday, June 9, 2018

Fasting And Stem Cell Function

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In mice, a 24 hour fast improves the function of intestinal stem cells through effects on fatty acid oxidation (FAO).  Genetic knockout e...
Saturday, April 28, 2018

Chemotherapy Conundrum

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Chemotherapy is usually effective against cancer, but recurrence/resistance can occur.  Senescence – stopping of cell cycle and cell growth...
Saturday, March 31, 2018

Human Colon Reconstruction In A Mouse Model

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This is an exciting paper , in which human colon stem cells were used to reconstruct human colon epithelium – a step toward colon reconst...
Saturday, March 24, 2018

Cancer Stem Cells And Lipid Metabolism

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Cancer stem cells are highly dependent upon lipid metabolism; abstract: Cancer stem cells (CSCs) are an uncommon subset of tumor cell...
Tuesday, February 6, 2018

Regenerating Human Skin

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Stem cell therapy is an exciting approach for many human disorders; here we see an example of an entire epidermis (skin) being regenerated ...
Tuesday, December 12, 2017

Blue Light Activation Of Gene Expression

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Here is an interesting study in which human cells are modified so that they react to blue light exposure with altered gene expression.  ...
Wednesday, November 15, 2017

Potential Stem Cell Therapeutic Engineering

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This paper discusses some advances in genetic engineering of cells, which may be of use “to develop innovative stem cell-based therapeutic...
Thursday, October 26, 2017

Cancer Stem Cell Switch

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By Philippe Hupé - Emmanuel Barillot, Laurence Calzone, Philippe Hupé, Jean-Philippe Vert, Andrei Zinovyev, Computational Systems Biology...
Friday, September 22, 2017

iPS Cells Against Parkinson's Disease

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By Y tambe - Y_tambe's file, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=3210604 Induced pluripotent stem (iPS)...
Saturday, February 6, 2016

Forever young versus the self-destruction of the body

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The Daily Beast named 2015 " The Year We Decided to Live Forever ". Why? Because the rich people (e.g., Peter Thiel, Sergey ...