Showing posts with label cancer. Show all posts
Showing posts with label cancer. Show all posts
Thursday, January 23, 2025

Myoststin Knockout Improves Cachexia And Inhibits Tumor Growth

›
Cachexia- induced muscle wasting is a problem in cancer. This paper tests the hypothesis that knocking out myostatin expression could help...
Thursday, December 19, 2024

Identifying And Targeting Cancer Stem Cells

›
Here is a paper from several years ago demonstrating further identification of (colon) cancer stem cells, with information on targeting suc...
Thursday, March 21, 2024

Coffee And Cancer Risk

›
Here is a paper on coffee consumption and cancer risk from several years ago,  Bottom like is that there doesn't seem to be a big effec...
Thursday, June 23, 2022

Wnt Signaling And TB

›
Here is an interesting paper from several years ago discussing a potential link between a signaling pathway more commonly associated with (...
Thursday, August 19, 2021

Exercise, DKK1, SFRP1, And Cancer

›
Here is a study on breast cancer patients suggesting that physical activity/exercise can reduce blood levels of cell signaling factors, on...
Thursday, February 18, 2021

Prevent Aging With Stem Cell Rejuvenation?

›
Discussion of a possible anti-aging approach , abstract: Characterized by dysfunction of tissues, organs, organ systems and the whole o...
Thursday, December 12, 2019

Epigenomics And Cancer Heterogeneity

›
There can be considerable heterogeneity in cancers, and this can contribute to progression and resistance to therapy.  This heterogeneity c...
Thursday, November 14, 2019

Warburg Effect And Some Possible Cancer Treatments

›
The Warburg effect is important in cancer, since cancer cells rely more heavily than do normal cells on glycolysis for energy production.  ...
Thursday, August 15, 2019

Cancer Incidence In Different Parts Of The USA

›
Different forms of cancer seem more prevalent in some areas of the USA compared to others.  For example, read here.  Part of abstract: ...
Friday, February 15, 2019

More On Tumor Immune Evasion

›
One mechanism of tumor immune evasion (at least in mice) is discussed here , abstract: Conventional type 1 dendritic cells (cDC1) are ...
Friday, December 14, 2018

Genetic Variation And Immune Checkpoint Therapy

›
Patient response to immune checkpoint therapy is influenced by patient genotype .  It may be necessary to determine individual genetic vari...
Monday, October 29, 2018

Colobronchial Fistula.

›
Here we see why investigating strange physical symptoms is important: a case of a colobronchial fistula.  
Tuesday, September 25, 2018

Multiple Myeloma Treatment Options

›
Treatment options for relapsing/progressing multiple myeloma ; abstract: Despite enormous advances, management of multiple myeloma (MM...
Sunday, September 23, 2018

Immune Checkpoint Inhibitor Therapy Biomarkers

›
Immune checkpoints dampen the immune system’s ability to detect and fight cancer; thus, inhibits of such checkpoints, usually antibodies to...

CDK8 Inhibitors And Cancer

›
CDK8 seems to have dual functions with respect to cancer, and investigating these roles, for potential therapeutic applications, will requi...
Thursday, September 20, 2018

Liver Cancer, Males Vs. Females, And ZebraFish

›
At left, adult female zebrafish. By Azul (Own work) [Copyrighted free use], via Wikimedia Commons Liver cancer is more prevalent in m...
Friday, August 17, 2018

Cancer Stem Cells And Lipid Metabolism

›
Cancer stem cells seem to have an increased reliance on lipid metabolism , which can be a target for anti-cancer therapy.  I wonder if this...
Friday, June 29, 2018

Cytoplasmic DNA And Metastasis

›
Chromosomal instability results in DNA in the cytoplasm, which is of course not normal, DNA being normally found only in the nucleus.  This...
Monday, June 25, 2018

p53 Inhibits CRISPR-Cas9 Engineering In Human Pluripotent Stem Cells

›
Human pluripotent stem cells are difficult to engineer with the CRSPR system compared to other cell types, which is unfortunate given the g...
Thursday, June 21, 2018

Cancer Immunotherapy: The Systemic Response

›
An article  on cancer immunotherapy ; the abstract: Immune responses involve coordination across cell types and tissues. However, studi...