Showing posts with label brain. Show all posts
Showing posts with label brain. Show all posts
Thursday, June 22, 2023

What We Eat Is What We Think?

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Consider that diet can affect your gut microbiome.  Consider also that gut bacteria produce short chain fatty acids from dietary fiber, so ...
Thursday, September 15, 2022

Genome Editing In The (Mouse) Brain

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Here is a paper from several years ago discussing a fascinating and very promising finding.  We'll need to take a look at any subseque...
Thursday, January 23, 2020

Immune Defect As A Cause Of Alzheimer's Disease

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An interesting hypothesis , abstract: Inflammation is an immune activity designed to protect the host from pathogens and noxious agents...
Sunday, February 3, 2019

Blood-Brain Barrier And Neurodegeneration

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The blood-brain barrier is important for maintaining the health and proper function of the central nervous system, and this barrier breaks ...
Friday, August 17, 2018

Immune Memory And Neurological Disease

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Innate immune memory in the brain shapes neurological disease hallmarks ; abstract: Innate immune memory is a vital mechanism of myelo...
Friday, June 29, 2018

Genetic Structure Affected By Maternal Care (In Mice)

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Early life experiences, such as maternal care, alters the genetic structure in neurons in mice, with mobile genetic elements seemingly re...
Tuesday, June 12, 2018

Prior Expectations Primes The Brain

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The paper linked here shows that prior expectation of an external stimulus “tunes” the brain to expect that stimulus and thus affects the ...
Saturday, June 9, 2018

Wnt And Alzheimer's Disease

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Promoting Wnt signaling against Alzheimer’s.   Abstract: This Editorial highlights an article in the current issue by Tapia-Rojas and ...
Sunday, May 20, 2018

Clinical Benefits Of Marijuana?

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Please note that this blog does not take sides in the legalization debate, and certainly does not condone or promote illegal drug use in...
Saturday, May 19, 2018

Dietary Polyphenols And Preventing Cognitive Decline With Aging

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Dietary polyphenols , by affecting cell signaling, can prevent declining nerve growth in adults and counteract cognitive decline due to age...
Sunday, April 29, 2018

Cognitive Decline With Aging

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Experiments with mice suggest that the aging brain accumulates astrocyte cells with an inflammatory phenotype that lose their normal func...
Wednesday, April 25, 2018

A Judicious Update: Alzheimer’s Disease

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By ADEAR: "Alzheimer's Disease Education and Referral Center, a service of the National Institute on Aging." - http://www.n...
Tuesday, April 24, 2018

Serotonergic Psychedelics And Personality

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For general interest , abstract: Serotonergic psychedelics act as agonists at cortical 5-HT2A receptors and seem to induce personalit...
Wednesday, April 18, 2018

Microglia Cells In Brain Disease

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By Frontiers in cellular neuroscience - http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00049/full, CC BY 3.0, https://commons....
Sunday, April 8, 2018

High Fat Diet And the Aging Mouse Brain

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A high fat diet seems not to be very good for aging of the mouse brain .  Fasting and a low fat diet seemingly have different effects.  A...
Wednesday, March 21, 2018

Wnt Signaling And Brain Injury Repair

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Wnt signaling has been shown to contribute to blood vessel repair after traumatic brain injury .  Thus suggests to me that Wnt agonists (ag...
Monday, March 12, 2018

The Decrepit Adult

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Contrary to previous belief, it seems that in humans, formation of new neurons in the hippocampus, important for learning and memory, essen...
Friday, March 9, 2018

Beta-Catenin In Stress And Depression

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The beta-catenin protein, integrally involved in Wnt signaling, influences stress and depression .  Abstract: Beta-catenin is a prot...
Wednesday, February 28, 2018

Cosmic Rays And Cognitive Decline (And A Hypothesis)

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By NASA/JPL-Caltech/SwRI - http://photojournal.jpl.nasa.gov/jpeg/PIA16938.jpg, Public Domain, https://commons.wikimedia.org/w/index.php?c...
Wednesday, February 21, 2018

Microbiome And Sex-Specific Brain Development

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The microbiome can affect microglia development in a sex-specific manner , which has implications for brain development and function.  This...