Showing posts with label Alzheimer's disease. Show all posts
Showing posts with label Alzheimer's disease. Show all posts
Thursday, January 23, 2020

Immune Defect As A Cause Of Alzheimer's Disease

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An interesting hypothesis , abstract: Inflammation is an immune activity designed to protect the host from pathogens and noxious agents...
Wednesday, February 13, 2019

Nervous System Immune Cells

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There are distinct populations of central nervous system immune cells comparing states of health, aging, and disease Alzheimer's disea...
Sunday, February 3, 2019

Blood-Brain Barrier And Neurodegeneration

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The blood-brain barrier is important for maintaining the health and proper function of the central nervous system, and this barrier breaks ...
Friday, August 17, 2018

Immune Memory And Neurological Disease

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Innate immune memory in the brain shapes neurological disease hallmarks ; abstract: Innate immune memory is a vital mechanism of myelo...
Wednesday, August 15, 2018

Wnt Signaling, DKK3, and Alzheimer's Disease Models

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More evidence of  dysfunctional Wnt signaling being involvedin the pathogenesis of Alzheimer’s disease (AD) is here , with the finding tha...
Wednesday, August 1, 2018

Down Syndrome and Alzheimer's

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Down syndrome patients accumulate brain features characteristic of Alzheimer's disease by age 40, and most go on to develop dementia.  ...
Friday, July 20, 2018

Extracellular Vesicles And Neurodegeneration

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Extracellular vesicles have effects on Alzheimer’s disease and other neurodegenerative diseases, mostly negative but possibly also some pos...
Saturday, June 30, 2018

Strains Of Misfolded Proteins And Alzheimer's Disease

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Neurodegenerative diseases tend to involve tangled misfolded proteins, and for some diseases “strains” are already known.  Here we see that...
Saturday, June 9, 2018

Wnt And Alzheimer's Disease

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Promoting Wnt signaling against Alzheimer’s.   Abstract: This Editorial highlights an article in the current issue by Tapia-Rojas and ...
Wednesday, April 25, 2018

A Judicious Update: Alzheimer’s Disease

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By ADEAR: "Alzheimer's Disease Education and Referral Center, a service of the National Institute on Aging." - http://www.n...
Monday, April 2, 2018

Aging And Dementia Links

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Aging and dementia has common links, including the mitochondrial α-F1 -ATP synthase (ATP5A), which can be a target for the Alzheimer's...
Tuesday, February 13, 2018

Janus-Faced Wnt Signaling

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Deregulated Wnt signaling leads to certain types of cancer, particularly colorectal cancer.  But Wnt signaling is two-faced, Janus-faced,...
Saturday, February 10, 2018

More On Mitochondria And Alzheimer's Disease

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It has been shown that the stimulation of certain mitochondrial functions can increase the fitness and lifespan of a worm model of Alzheim...
Wednesday, January 17, 2018

APOE4 And Late-onset Alzheimer Disease

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This link is to another paper showing an association between APOE4 and late-onset Alzheimer disease.   Understanding how the APOE4 gene var...
Wednesday, January 3, 2018

Diabetes Drugs Against Alzheimer’s Disease

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Some findings of interest , relevant sections: Studies in a mouse model of Alzheimer’s disease (AD) have shown how a drug that was orig...
Thursday, July 27, 2017

Alzheimer's Disease-Cancer Link

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First described case of Alzheimer's disease. By Unknown - Unknown, Public Domain, https://commons.wikimedia.org/w/index.php?curid=159...
Tuesday, February 7, 2017

Grapes Against Alzheimer's Disease

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By Fir0002 - Own work, GFDL 1.2, https://commons.wikimedia.org/w/index.php?curid=135219 Another benefit of grapes , relevant sections fro...